Thiosulphate sulfurtransferase, conserved site <p>Synonym(s): Rhodanese</p><p>Thiosulphate sulphurtransferase (<db_xref db="EC" dbkey="2.8.1.1"/>) is an enzyme which catalyses the transfer of the sulphane atom of thiosulphate to cyanide, to form sulphite and thiocyanate. In vertebrates, rhodanese is a mitochondrial enzyme that is involved in forming iron-sulphur complexes and cyanide detoxification. A cysteine residue takes part in the catalytic mechanism [<cite idref="PUB00003557"/>, <cite idref="PUB00000494"/>]. Some bacterial proteins may also express sulphotransferase activity. These include, SseA from <taxon tax_id="1769">Mycobacterium leprae</taxon> and <taxon tax_id="562">Escherichia coli</taxon>, <taxon tax_id="354">Azotobacter vinelandii</taxon> rhdA, <taxon tax_id="1836">Saccharopolyspora erythraea</taxon> cysA [<cite idref="PUB00002108"/>] and <taxon tax_id="1140">Synechococcus sp.</taxon> (strain PCC 7942) rhdA [<cite idref="PUB00002137"/>].</p>